PICSI IVF: Advanced Sperm Selection Technique in Fertility Treatment
Infertility can be difficult for couples and families, especially when pregnancy does not happen even after trying for a long time. Sometimes the quality of the sperm is the problem, not the egg. PICSI IVF is a cutting-edge fertility method that increases the likelihood of successful fertilisation and pregnancy by choosing healthier and more mature sperm.
What Is PICSI IVF?
PICSI IVF stands for Physiological Intracytoplasmic Sperm Injection. It is an advanced version of the ICSI technique used in IVF treatment.
In conventional IVF or ICSI, sperm are selected mainly based on their appearance and movement. However, some sperm may look normal but still carry DNA damage. PICSI IVF helps select sperm that are naturally mature and genetically healthier.
How Does PICSI IVF Work?
The natural material that surrounds a woman’s egg is called hyaluronic acid. It can only bind to mature, healthy sperm during spontaneous conception.
Sperm that adhere to hyaluronic acid are chosen for PICSI IVF because they are more likely to have high-quality DNA.
Hyaluronic Acid's Function
The natural material that surrounds a woman’s egg is called hyaluronic acid. It can only bind to mature, healthy sperm during spontaneous conception.
Sperm that adhere to hyaluronic acid are chosen for PICSI IVF because they are more likely to have high-quality DNA.
Detailed PICSI IVF Procedure
- Standard IVF methods are used to extract eggs from the female partner.
- A sample of the male partner’s semen is given..
- A special PICSI dish coated with hyaluronic acid is prepared.
- Only sperm that bind naturally to the hyaluronic acid are selected.
- The selected sperm is injected into the egg.
- Fertilized eggs are monitored for embryo development.
- A healthy embryo is transferred into the uterus
Who Should Consider PICSI IVF?
PICSI IVF is usually recommended for couples facing male fertility issues or repeated IVF failures.
PICSI IVF may be suitable if:
- The male partner has poor sperm quality
- High sperm DNA fragmentation is present
- Previous IVF or ICSI cycles have failed
- Poor embryo quality was seen earlier
- Recurrent miscarriages have occurred
A fertility specialist decides whether PICSI IVF is appropriate after proper evaluation.
Benefits of Choosing PICSI IVF
PICSI IVF offers several advantages in selected fertility cases.
- Selection of mature and healthy spermImproved embryo quality
- Reduced sperm DNA damage
- Better implantation potential
- Lower risk of miscarriage
- Mimics natural sperm selection
Factors to Consider Before Choosing PICSI IVF
Before choosing PICSI IVF, couples should understand the following points:
- It may cost slightly more than standard ICSI
- It is mainly helpful in sperm-related infertility
- Success depends on egg quality and age
- Requires an advanced IVF laboratory
- Should be done only on a doctor’s recommendation
Success Rates of PICSI IVF
PICSI IVF does not guarantee pregnancy, but it can improve outcomes in specific cases.
Success depends on:
- Age of the woman
- Quality of eggs and sperm
- Uterine health
- Overall medical history
In cases of male infertility, PICSI IVF may lead to better fertilization and embryo development compared to standard techniques.
Potential Risks and Limitations of PICSI IVF
PICSI IVF is safe but has some limitations:
- Not useful if infertility is not related to sperm quality
- Slightly higher treatment cost
- Requires skilled embryologists
- Pregnancy cannot be guaranteed
There is no evidence that PICSI IVF increases risks to the baby.
Is PICSI IVF Right for You?
PICSI IVF may be right for you if:
- You have had failed IVF attempts
- Sperm quality issues are present
- Your doctor recommends advanced sperm selection
- You want a more natural fertilization approach
A fertility specialist can guide you based on your medical condition.
Why Choose Lifeline IVF Hospital?
Lifeline IVF Hospital offers advanced fertility care with a strong patient-centered approach, ensuring every couple receives compassionate and personalized treatment. The hospital is supported by experienced fertility specialists and state-of-the-art IVF laboratory facilities that meet international standards. Each patient is given a customized treatment plan based on their medical history and fertility needs, with complete transparency and ethical practices at every stage of care. Lifeline IVF Hospital also has proven expertise in advanced fertility techniques, including PICSI IVF, helping couples achieve better outcomes with confidence and trust.
Conclusion
PICSI IVF is an advanced sperm selection technique that helps improve fertilization and embryo quality in certain infertility cases, especially those related to male factors. When recommended by a fertility expert, it can significantly improve the chances of pregnancy.
With expert guidance and advanced fertility care at Lifeline IVF Hospital, couples can take a confident step toward parenthood.
FAQs
Is PICSI IVF different from ICSI?
Yes, PICSI IVF selects sperm using hyaluronic acid, while ICSI selects sperm mainly based on appearance.
Is PICSI IVF safe?
Yes, PICSI IVF is safe and widely used in fertility treatment.
Does PICSI IVF increase pregnancy chances?
It may improve pregnancy chances in cases related to poor sperm quality.
Who decides if PICSI IVF is needed?
A fertility specialist makes this decision after reviewing fertility tests and medical history.
Is PICSI IVF painful?
No, PICSI IVF is performed in the laboratory and does not cause extra pain.
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In Vitro Fertilization (IVF)
Intrauterine Insemination (IUI)
ICSI (Intracytoplasmic Sperm Injection)
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Female Infertility Solutions
Donor Egg and Donor Sperm Programs
Embryo Freezing & Fertility Preservation
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